Gentamicin

Specimen requirements

Adult sample type: Serum (gold/yellow top SST)

Paediatric sample type: Plasma (orange top paediatric tube)

Collection requirements: No special requirements

Cost

Price on application

Turnaround time

Please see Turnaround times

Analytical method

Immunoassay - Particle-enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

Analysis undertaken at these site(s)

John Radcliffe Hospital

Reference intervals

If continuing Gentamicin beyond 48 hours:

Once daily dosing (5-7mg/kg): interpret level using Nomogram in 'Antibiotic Guidelines, Intravenous Gentamicin in Adults' on the Clinical Intranet.

Dosing in renal impairment (3mg/kg): repeat dose when TROUGH is less than 2 mg/L

In endocarditis, if synergy required:

• Trough: less than 1 mg/L
• Peak (1 hour POST dose): 3-5 mg/L