Oxford Adult Cystic Fibrosis Centre research

Current research projects

Exploring clinicians' approach to weight gain in people with CF on CFTR modulator treatment - a qualitative study run by Joanna Snowball, Dietitian at OACFC and funded by the NIHR Oxford Biomedical Research Centre. J.E. Snowball, W.G. Flight, L. Heath et al., A paradigm shift in cystic fibrosis nutritional care: Clinicians’ views on the management of patients with overweight and obesity, Journal of Cystic Fibrosis.

Antibiotic Resistance in the Microbiome Oxford (ARMORd Study) - collaboration with Nuffield Department of Medicine, University of Oxford.

ACtiF Study - collaboration with Dr Martin Wildman and colleagues at the University of Sheffield. This research study has developed the CFHealthHub programme - a country-wide collaborative to learn how to support people with CF with adherence to nebulised therapies. Participation in CFHH provides a contribution to other studies across the CF research community.

National efficacy effectiveness CFTR modulators optimisation programme (NEEMO) - this study, hosted by the CFHealthHub platform, looks to explore the impact of adherence to nebulised therapies in people with CF who are prescribed CFTR modulators.

CF Storm - this multicentre NIHR and HTA funded study is exploring the impact of discontinuing nebulised mucolytic treatments including DNase and Hypertonic Saline in CF patients prescribed Kaftrio.

Further information

If you are interested in finding out more about opportunities to get involved with research studies, please ask the team at your clinic visit.

For more information about Research at Oxford University Hospitals, please visit:

Research

Peer-reviewed research

Warnock L, Gates A. Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis. Cochrane Database of Systematic Reviews 2015, Issue 12. Art. No.: CD001401. DOI: 10.1002/14651858.CD001401.pub3. Accessed 19 April 2022.